The Anjozorobe forest corridor is a site which is recognized for its remarkable biodiversity. The last census conducted in 1999, more than 423 plant species were counted in the forest of which 65% are endemic and 11 species of lemurs have been identified.

The Anjozorobe forest is part of a branch of the eastern rainforest that runs along the Angavo scarp. The forest lies on metamorphic rock, and the terrain is mountainous and deeply dissected, with steep eroded slopes. The Mananara river, a tributary of the Betsiboka, flows across the western part of the site, which is also crossed by other rivers such as the Sahavila. The main vegetation is mid-altitude, dense, humid evergreen forest.